Background: The prevalence of potential risk factors for postoperative cough after thyroidectomy remain\nunknown. The current study aimed to research postoperative cough in patients undergoing thyroid surgery\nprospectively.\nMethods: Adult patients who underwent primary thyroid surgery were selected prospectively. Data regarding age,\nsex, BMI, pathology and surgical procedure were collected and analyzed. The Leicester Cugh Questionnaire (LCQ)\nwas required to be completed by all patients before operation, 2 weeks and 4 weeks after operation.\nResults: There were 1264 patients enrolled in total. Eleven patients with vocal cord paralysis were excluded. In\npatients with benign disease, postoperative cough occurred in 61 patients, with an prevalence rate of 17. 0%\ncompared to an prevalence rate of 33.1% in patients with malignant disease; the difference was significant. For\nbenign patients, the factors of smoking and operation time were independently related to the occurrence of\npostoperative cough. For malignant patients, the factors of smoking, operation time, operation extent, and the\nnumber of positive nodes at level 6 were independently related to the occurrence of postoperative cough. There\nwas no significant difference regarding the LCQ score in patients with benign or malignant disease at the\npreoperative and the postoperative 4-week time periods. Patients with malignant disease had a significantly lower\nLCQ score than patients with....................
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